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Menopause and Natural Hormone Replacement Therapy

Understanding Menopause - Types Of Menopause

· Natural Menopause
· Induced Menopause
· Premature Menopause
· Perimenopause


Natural Menopause - The definition of natural menopause according to the Council of affiliated Menopause Societies (CAMS) defines spontaneous menopause as the following; "the permanent sensation of menstruation resulting from the loss of ovarian follicular activity. Natural menopause is recognized to have occurred after 12 consecutive months of amenorrhea (stopped periods) for which there is no other pathologic or biologic cause." To put it very simply, menopause is the stop (pause) of your periods (menses).

In the Western world the mean age for menopause is 51.4 year's, with a range between 40 and 58 years. What makes menopause different for women today than for their great grand parents is the fact that woman now can expect to live another thirty years after menopause.

Induced Menopause - Menopause can also be Induced or commonly referred to as surgical menopause is defined by CAMS as "the cessation of menstruation that follows either surgical removal of both ovaries (with or without hysterectomy) or iatrogenic ablation of ovarian function (e.g. by chemotherapy or radiation)". Women whom have the misfortune to undergo surgically induced menopause develop immediate estrogen withdrawal and deficiency symptoms. What makes the transition so difficult is the fact that one day you have a normal menstrual cycle, the next day you have none whatsoever. With natural menopause there is a gradual reduction of estrogen thus the symptoms from induced menopause both physically and psychologically are much more intense.

Abstracts:
Physiologic aspects of natural and surgical menopause. J Reprod Med 2001 Mar;46(3 Suppl):307-15

Issues surrounding surgical menopause. Indications and procedures J Reprod Med 2001 Mar;46(3 Suppl):297-306

Premature Menopause - Premature Menopause or premature ovarian failure (POF) is a third condition which results in cessation of menstruation defined by CAMS "as menopause that occurs at an age less then two standard deviations below the mean estimated age for the reference population thus the age of 40 or less is considered POF". Premature spontaneous ovarian failure clinical trial data suggest that the incidence of POF in the US women is about 1%. What differentiates POF with natural spontaneous menopause have an estimated 5% to 10% chance of spontaneous pregnancy.

Causes of POF, which are not due to induced menopause, as discussed above include:

Genetic Irregularity: Defects on an X Chromosoome

Autoimmune Disorder: Studies have shown that up to two-thirds of the women with premature ovarian failure have it due to an autoimmune disorder. In the case of premature menopause, you may have antibodies to your own ovarian tissue, to your endometrium, or to one or more of the hormones regulating ovulation. These antibodies attack your reproductive system, and may interfere with and ultimately destroy your ovarian function.

Women whom reach menopause prematurely, that is before the age of 40 has a two-fold increase in mortality rate. Thus the use of HRT or Birth control pills should be seriously considered due to the long-term health implications.

Perimenopause: Can be viewed as the actually time in ones life when you are going through menopause According to CAMS Perimenopause is defined as "the period immediately prior to menopause (when the endocrinologic,biologic, and clinical features of approaching menopause commence) and the first year after menopause." According to the North American Menopause society "the median age for Perimenopause is 47.5 years. For most women this period last 4 years. With 90% of women experiencing menstrual irregularity and 10% cease menstruation abruptly.

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Disclaimer: The information contained on this website has not been evaluated by the FDA. This information is not intended to treat, diagnose, cure or prevent any disease. All material provided in the Dr. Brizel's web site is provided for educational purposes only. Always seek the advice of your physician or other qualified health care provider with any questions you have regarding a medical condition, and before undertaking any diet, exercise or other health program.

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