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Premenstrual
Syndrome (PMS) & Premenstrual Dysphoric Disorder (PDD)
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| Premenstrual
Syndrome (PMS) & Premenstrual Dysphoric Disorder (PDD) -
Targeted Vitamin, Mineral and Essential Fatty Acids |
First
all women with PMS should get themselves on a good multivitamin
for women. In our center the following supplements have been used
successfully to reduce and eliminate symptoms of PMS;
- Vitamin
E 400 to 800u (preferred form natural mixed tocopherol)
- B6
(pyridoxine) take 50 to max of 200 mg. Use of B6 has been reported
to help symptoms of PMS in dozens of studies since 1970's. In
our clinic we additional give the active form of B6 pyridoxal-5-phosphate
for those who have a difficult time with the conversion of B6
to its active form. Also we give a B-Complex in addition. Too
much B6 in excess of 250mg for several months has been reported
to cause some neurological problems but this problem is avoided
if doses are kept lower and a B complex is given in conjunction.
- Magnesium
preferably in the form of magnesium glycinate, which provides
better absorption. This does have a laxative effect so it might
be better taken in multiple doses. Dosage recommended is 600mg
twice a day
- Gamma-Linoleic
Acid (GLA) found as borage or evening primrose oil a dosage of
400mg of GLA should be taken
Amino
Acids
The two amino acids that we use in PMS are for specific problems.
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Taurine 1000 to 2000mg has been used as a natural diuretic to
assist with fluid retention which is common in PMS
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S-Adenosylmethionine (SAM) formed in the body by combining the
essential amino acid methionine with adenosyl-triphosphate (ATP).
Supplementing the diet with SAM in depressed patients results
in increased levels of serotonin, dopamine, and phosphatidylserine.
It improves binding of neurotransmitters to receptor sites, which
causes increased serotonin and dopamine activity and improved
brain cell membrane fluidity, all resulting in significant clinical
improvement. We have use SAM as an initial treatment of or patients
with the more severe form of PMS called premenstrual dysphoric
syndrome. In dose of 400mg twice a day use of the conventional
drugs can be avoided since this is much better tolerated then
anti-depressants. Also this supplement can be use a an adjunct
to the SSRI since the onset of therapeutic action is more rapid
achieving effect in 4 to 7 days whereas SSRI drugs take up to
4 weeks. The problem with the use of Sam is the cost could be
prohibitive for some patients.
| Premenstrual
Syndrome (PMS) & Premenstrual Dysphoric Disorder (PDD) |
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